"Third spacing" is the abnormal accumulation of fluid into an extracellular and extravascular space. In medicine, the term is often used with regard to loss of fluid into interstitial spaces, such as with burns or edema, but it can also refer to fluid shifts into a body cavity (transcellular space), such as ascites and pleural effusions. With ...
The extracellular matrix (ECM) is a complex, interconnected meshwork of connective tissue that supports and provides a structural framework for cells and tissue organization. It is present in the interstitial space and it consists of a gel-like combination of polysaccharides, glycoproteins and proteoglycans.
Extracellular fluid (ECF) denotes all body fluid outside the cells of any multicellular organism. Total body water in healthy adults is about 60% (range 45 to 75%) of total body weight; women and the obese have a lower percentage than lean men.  Extracellular fluid makes up about one-third of body fluid, the remaining two-thirds is intracellular fluid within cells.
It’s simple. Extracellular fluid usually is the bodyfluid which is outside the cell. Everything except this is intracellular fluid. And the interstitial fluid is something that is present around the tissue cells of multicellular animals. So basica...
In this video we discuss what is the extracellular matrix and what is interstitial fluid. We also cover some of the functions of the extracellular matrix as well as the function of interstitial fluid.
Paul Andersen explains the importance and location of interstitial fluid. He describes both the hydrostatic and osmotic pressures that move fluid between the interstitial fluid and the capillary ...
Extracellular fluid (ECF) surrounds all cells in the body. Extracellular fluid has two primary constituents: the fluid component of the blood (called plasma) and the interstitial fluid (IF) that surrounds all cells not in the blood. Intracellular Fluid. The ICF lies within cells and is the principal component of the cytosol/cytoplasm.
The interstitial compartment is the space between the capillaries and the cells. Fluids support the matrix and cells within the interstitial space. The intracellular compartment is separated from the interstitial space by a cell membrane. This membrane is freely permeable to water but not to small- or large-molecular-weight particles.
Interstitial space: The fluid filled areas that surround the cells of a given tissue; also known as tissue space. Mentioned in: Lymphedema
Residual plasma and extracellular volumes were established by tracer distribution, whereas interstitial volumes could be derived by subtracting the residual plasma from the total extracellular space. These volume fractions are important input parameters in the PBPK model and are necessary to more accurately describe distribution to and within ...