Web Results

www.nature.com/articles/s41588-018-0183-z

Aug 13, 2018 ... Polygenic score derivation. Polygenic scores provide a quantitative metric of an individual's inherited risk based on the cumulative impact of many ...

www.ahajournals.org/doi/10.1161/ATVBAHA.120.314856

Sep 22, 2020 ... Genome-wide polygenic scores (GPSs) are a new quantitative predictor of inherited risk, integrating information from many common sites of DNA ...

www.ahajournals.org/doi/10.1161/STROKEAHA.119.027520

Jan 31, 2020 ... This study showed that a genome-wide polygenic score derived from >350 000 single-nucleotide polymorphisms was more strongly associated ...

pubmed.ncbi.nlm.nih.gov/30104762

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nat Genet. 2018 Sep;50(9):1219-1224.

en.wikipedia.org/wiki/Polygenic_score

In genetics, a polygenic score, also called a polygenic risk score (PRS), genetic risk score, or genome-wide score, is a number that summarises the estimated ...

www.genome.gov/Health/Genomics-and-Medicine/Polygenic-risk-scores

Aug 11, 2020 ... A polygenic risk score is one way by which people can learn what their risk of ... a polygenic risk score comes from large scale genomic studies.

www.sciencedirect.com/science/article/pii/S0735109720356448

Aug 11, 2020 ... Genome-wide polygenic scores (GPS) integrate information from many common DNA variants into a single number. Because rates of coronary ...

www.kidney-international.org/article/S0085-2538(20)30641-4/fulltext

Jun 12, 2020 ... Polygenic scores measure the cumulative impact of common variants on the risk of certain disorders with the impact of individual variants ...

genomemedicine.biomedcentral.com/articles/10.1186/s13073-020-00742-5

May 18, 2020 ... Genome-wide association studies have shown unequivocally that common complex disorders have a polygenic genetic architecture and have ...

www.pnas.org/content/117/32/18924

Aug 11, 2020 ... The development of genome-wide genetic association studies (GWAS) raised the hope that it would be possible to identify single polymorphic ...