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Liver cancer is difficult to diagnose in early stages, as it often has no symptoms, and it is rare that medical staff are able to feel tumors from outside the body, according to MD Anderson Cancer Center. The tumor's development causes symptoms, but by then the staging is often advanced.


The difference between stage 4 liver cancer and stage 3 liver cancer is that in stage 4A, the cancer has spread to local lymph nodes, reports the American Cancer Society. In the more advanced stage 4B, the cancer has metastasized to distant organs. In stage 3 liver cancer, the cancer has not spread


One symptom of liver cancer is pain in the right shoulder blade or in the abdomen, according to the American Cancer Society. A person who is suffering from late-stage liver cancer might have chronic cirrhosis or hepatitis, which can make a person feel worse than usual.


Stages III and IV are the final stages of liver cancer. During these stages, there may be multiple cancerous tumors and a spread of cancer to blood vessels beyond the liver to lymph nodes or to other body parts, such as the bones or the lungs, according to Cleveland Clinic.


Some symptoms of end-stage liver cancer include worsening jaundice, drowsiness and confusion, according to Merck Manuals. Fatigue, pain, changes in appetite and difficulty breathing are additional symptoms of end-state cancer, reports the American Cancer Society.


End-stage liver disease refers to an advanced stage of liver tissue damage, where the liver fails to perform its functions, according to eMedicineHealth. It is also known as liver failure. Although rarely reversible, the treatment of end-stage liver disease only prevents further liver damage, accord


The four stages of liver disease are inflammation, fibrosis, cirrhosis and liver failure, according to the American Liver Foundation. Whether the liver is infected, injured by toxins such as alcohol or chemicals, or under attack from a patient's own immune system, liver disease progresses in much th


End-stage symptoms of cancer are fatigue, pain, appetite loss and respiratory problems, explains the American Cancer Society. Not only do patients struggle to breathe, but their breathing changes, becoming moist and congested.


The American Society of Clinical Oncology explains that the end stage of cancer is diagnosed when the cancer has spread to other parts of the body. This stage is also called stage 4, advanced or metastatic cancer.


Loss of appetite, unexplained weight loss, nausea, vomiting and feeling full after eating a small amount are some early signs of liver cancer, according to the American Cancer Society. Generally, the symptoms of liver cancer are not present until the disease is in its advanced stages.