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However, if a person’s choline levels drop too low, he or she can experience muscle and liver damage as well as deposits of fat in the liver (a condition called nonalcoholic fatty liver disease that can damage the liver). What are some effects of choline on health? Scientists are studying choline to better understand how it affects health.


These side effects are not known to be life threatening or dangerous, and typically consist of unpleasant or annoying outcomes. The most common side effects of an overdose in Choline can result in nausea, vomiting, diarrhea, sweating, and a fishy odor produced by the body.


Knott V, de la Salle S, Choueiry J, et al. Neurocognitive effects of acute choline supplementation in low, medium and high performer healthy volunteers. Pharmacol Biochem Behav. 2015;131:119-129 ...


When taken as directed by health professionals, choline is not associated with any harmful side effects. In very rare instances, excessive choline intake has been associated with increased body temperature, sweating, and loss of appetite. Choline should be taken earlier in the day, as it can interfere with sleep if consumed too close to bedtime.


Choline is a dietary supplement; essential for proper cell function. Choline benefits the heart, the liver and the neurological system. According to Linus Pauling Institute, choline is a precursor for acetylcholine, a neurotransmitter; a chemical located and released in the brain that allows impulse to pass from one nerve cell to another 1. A small amount of choline is synthesized by the body ...


In general, choline supplements, such as alpha-GPC and citicoline, are safe for most people and rarely associated with negative side effects. However, consuming too much choline may have unpleasant...


Some studies point to the fact that low levels of acetylcholine may lead to cognitive decline, including Alzheimer’s disease and senile dementia.


Choline supports several vital bodily functions and may offer a wide range of other health benefits, such as: Improving memory and cognition. Choline is an essential nutrient for brain development ...


Chronic constipation and/or gastroparesis. are very common symptoms of low acetylcholine. Poor digestion and poor absorption of critical nutrients are also a common symptom of low acetylcholine potentially leading to malnutrition. 4. Dry Eyes (“dry as a bone”):


Read more: How to Take Inositol & Choline Supplements. Choline's Side Effects. A study in the November 2015 edition of the American Journal of Clinical Nutrition found that choline had benefits, but only one unwanted effect 4. Some participants noted a negative change in their body odor.