Web Results

www.hss.edu/conditions_understanding-laboratory-tests-and-results-for-systemic...

Anti-Sm (anti-Smith, named for the first patient known to have this antibody) is associated with a speckled ANA pattern and is the antibody seen in most patients who do not have anti-dsDNA. Some patients have both anti-dsDNA and anti-Sm. Anti-Sm antibody binds to a protein that is attached to DNA.

labtestsonline.org/tests/anti-dsdna

The anti-double stranded DNA (anti-dsDNA) test is used to help diagnose lupus (systemic lupus erythematosus, SLE) in a person who has a positive result on a test for antinuclear antibody (ANA) and has clinical signs and symptoms that suggest lupus.. Typically, an ANA test is the first test performed to evaluate an individual for an autoimmune disorder.

www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/8178

A positive test result for double-stranded DNA (dsDNA) antibodies is consistent with the diagnosis of systemic lupus erythematosus. A reference range study conducted at the Mayo Clinic demonstrated that, within a cohort of healthy adults (n=120), no individuals between the ages of 18 and 60 (n=78) had detectable anti-dsDNA antibodies.

testdirectory.questdiagnostics.com/test/test-detail/255/dna-ds-antibody?cc=MASTER

DNA (ds) Antibody - dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with Mixed Connective Tissue Disease. Home . DNA (ds) Antibody. ... To interpret test results use the reference range in the laboratory report.

www.southtees.nhs.uk/.../pathology/tests/dna-antibody-anti-double-stranded-dna

However, anti-dsDNA antibodies are frequently found in patients with overlap symptoms between SLE and other autoimmune diseases.In different SLE patients, relative levels of anti-DNA antibody do not correlate well with relative disease activity although rapid rises in antibody levels in any individual patient do suggest increases in disease ...

www.ncbi.nlm.nih.gov/pmc/articles/PMC4648223

The modification is that anti-dsDNA antibody levels should be above laboratory reference range (or twice the reference range if tested by ELISA). The variability of different anti-dsDNA assays was highlighted in an article by Compagno et al. 21 published in the inaugural issue of Lupus Science & Medicine. The article described the clinical ...

www.labcorp.com/tests/096339/anti-dsdna-double-stranded-antibodies

Following levels of anti-DNA antibody may be of use in evaluating response to therapy, but should be regarded as a guide rather than a rigid dictator of treatment. Antibody levels correlate particularly well with activity of lupus nephritis. Procainamide and hydralazine may induce anti-DNA antibodies and antihistone antibodies.

neurology.testcatalog.org/show/ADNA

A positive test result for double-stranded DNA (dsDNA) antibodies is consistent with the diagnosis of systemic lupus erythematosus. A reference range study conducted at the Mayo Clinic demonstrated that, within a cohort of healthy adults (n=120), no individuals between the ages of 18 and 60 (n=78) had detectable anti-dsDNA antibodies.

www.thelupussite.com/forum/index.php?threads/anti-double-stranded-dna.11299

The values would be crucial in managing the disease activity because one can quantify the severity of the flare or the effectiveness of treatment. LabCorp changed it's reference range for the DS DNA in 2009. Believe Addendum: Jetster, the reference range you posted on your reply is the same values that my lab used from 2002 till sometime in 2009.

www.healthcare.uiowa.edu/path_handbook/handbook/test681.html

Double-stranded DNA (dsDNA) IgG antibodies are part of the American College of Rheumatology criteria for the diagnosis of systemic lupus erythematosus (SLE). dsDNA are detectable in approximately 85% of patients with untreated SLE and are rarely detected in other connective tissue diseases.