Web Results

www.ncbi.nlm.nih.gov/pmc/articles/PMC2858486

Specifically, defects in ribosome biogenesis or function appear to be capable of causing anemia and other hematologic phenotypes, defects in growth and ...

www.ncbi.nlm.nih.gov/pmc/articles/PMC2965583

Jan 11, 2010 ... In mammalian cells, this number is even higher; for example, a HeLa cell ... It is therefore somewhat surprising that some defects in ribosome ...

cmns.umd.edu/news-events/news/1999

Mar 31, 2014 ... Mutations in some of the proteins that make ribosomes cause disorders characterized by bone marrow failure and anemia early in life, followed ...

en.wikipedia.org/wiki/Ribosomopathy

Ribosomopathies are diseases caused by abnormalities in the structure or function of ... Prokaryotic and eukaryotic ribosomes both contain a scaffold of ribosomal RNA (rRNA) on w...

basergalab.yale.edu/news/ribosomopathy-reveals-decoding-defective-ribosomes-driving-human-dysmorphism

Mar 2, 2017 ... A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human ... In both cases, the mutations caused defects in ribosome function.

harrystylli.com/what-are-ribosomes-and-how-do-they-affect-health

Jan 22, 2019 ... Ribosomopathies are genetic defects that affect ribosome biogenesis. ... their well-documented function in protein production, ribosomes may ...

academic.oup.com/nar/article/48/3/1013/5539888

Jul 27, 2019 ... Ribosomopathies can be defined as diseases associated with a ... Research on the effects of ribosomal defects on ribosome function and cell ...

www.sciencedirect.com/science/article/pii/S0002929717300678

Mar 2, 2017 ... ... ribosome biogenesis and maturation. Classical ribosomopathies have been typically associated with bone marrow failure (BMF). Examples ...

cancerdiscovery.aacrjournals.org/content/7/10/1069

Oct 1, 2017 ... Ribosomopathies are a collection of syndromes with the shared underlying feature of defective ribosomal function or production. The majority of ...

www.tandfonline.com/doi/full/10.1080/21675511.2015.1025185

The historic idea that ribosomes function constitutively to translate the genetic code continues to be challenged. Even core ribosome components may exert ...