Blue sclera is a condition of the eyes in which the whites of the eyes are a bluish color. This eye condition is a risk factor for many other eye diseases like Marfan's syndrome and pseudoxanthoma elasticum.
Introduction: This information shows the various causes of Blue sclerae, and how common these diseases or conditions are in the general population.This is not a direct indication as to how commonly these diseases are the actual cause of Blue sclerae, but gives a relative idea as to how frequent these diseases are seen overall.. 1 disease that is "rare".
/ The Whites of My Eyes Have Turned Blue! Morning Rounds. The Whites of My Eyes Have Turned Blue! Written By: Virginia Miraldi, BA, Arun D Singh, MD, and Bennie H. Jeng, MD ... although renal and urinary calculi also are common. Blue pigmentation of the sclera and ears are often the earliest changes, with the arthritic complications usually ...
Blue (blue) sclera can be a symptom of a number of systemic diseases. "Blue sclera" is most often a sign of Lobstein-van der Heve's syndrome, which belongs to the group of constitutional defects of connective tissue, due to numerous genetic injuries. The type of inheritance is autosomal dominant, with high (about 70%) pervetrence.
Blue sclerae are most importantly associated with types I and II osteogenesis imperfecta. Blue sclera may also be associated with: Ehler's danlos syndrome pseudoxanthoma elasticum Marfan's syndrome Blue sclera may also be acquired through long-term use of corticosteroids. There is no specific treatment usually done for blue sclera.
Blue sclerae result from congenital thinning of the sclerae. The underlying epithelium shows through, giving a blue appearance. Blue sclerae are most importantly associated with types I and II osteogenesis imperfecta, the latter of which is fatal and thus not seen in adult practice.
Blue sclerae, especially at infancy, is the most visible ocular sign in osteogenesis imperfecta but it is not always present. It is also often present in normal infants. In some patients, it is present early but disappears later in life. Some patients have significantly lower ocular rigidity, corneal diameters, and decreased globe length.
What Causes Blue Sclera? Blue sclera, or a blue tint to the white's of a patient's eyes, can be caused by the disease osteogenesis imperfecta, according to Medline Plus. Osteogenesis imperfect is a congenital disease that is most commonly caused by a defect in the gene that codes for type 1 collagen.
Osteogenesis imperfecta (OI), also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily. The severity may be mild to severe. Other symptoms may include a blue tinge to the whites of the eye, short height, loose joints, hearing loss, breathing problems and problems with the teeth.
All types of OI have some degree of bone fragility and fracturing, and many have some degree of bone deformity. People with OI are more vulnerable to lung problems, including asthma and pneumonia. Viral and bacterial infections can become severe. In fact, respiratory failure is the most common cause ...