Doctors give trusted, helpful answers on causes, diagnosis, symptoms, treatment, and more: Dr. Bensinger on blue sclera differential diagnosis: Osteogenesis imperfecta amongst its other problems, produces a thinning of the white outer coat of the eyeball, the sclera. Because of this the dark inner lining, the uvea, adds its coloration to light striking the thinned sclera and the result is a ...
Blue sclerae were present in 93.4% of patients, dentinogenesis imperfecta was observed in 27.6% of patients, and wormian bones in 29.4% of them.[ncbi.nlm.nih.gov] The patient's mother also had blue sclera and a history of frequent fracture episodes until the age of 15 years. [ncbi.nlm.nih.gov] Her mother appeared small stature, frequent fractures, blue sclera, and deformity of extremities.
/ The Whites of My Eyes Have Turned Blue! Morning Rounds. The Whites of My Eyes Have Turned Blue! Written By: Virginia Miraldi, BA, Arun D Singh, MD, and Bennie H. Jeng, MD ... The Differential Diagnosis. ... Blue pigmentation of the sclera and ears are often the earliest changes, with the arthritic complications usually presenting after the ...
Blue Sclera - link.springer.com. Differential Diagnosis Pediatric and orthopedic evaluations should be considered to exclude inherited causes of blue sclera and to identify systemic manifestations of disease. For instance, brittle cornea syndrome is characterized by blue sclera, brittle cornea, and …
Introduction: This information shows the various causes of Blue sclerae, and how common these diseases or conditions are in the general population.This is not a direct indication as to how commonly these diseases are the actual cause of Blue sclerae, but gives a relative idea as to how frequent these diseases are seen overall.. 1 disease that is "rare".
Blue sclera is a condition of the eyes in which the whites of the eyes are a bluish color. This eye condition is a risk factor for many other eye diseases like Marfan's syndrome and pseudoxanthoma elasticum.
Doctors give trusted, helpful answers on causes, diagnosis, symptoms, treatment, and more: Dr. LaBarbera on blue sclera differential: This usually refers to thin sclera, thin enough so that the blueish hues of the darker inner eye can be seen. Blue sclera can be seen with simple aging, ocular abnormalities like scleritis or more systemic conditions like osteogenesis imperfecta.
Blue (blue) sclera can be a symptom of a number of systemic diseases. "Blue sclera" is most often a sign of Lobstein-van der Heve's syndrome, which belongs to the group of constitutional defects of connective tissue, due to numerous genetic injuries. The type of inheritance is autosomal dominant, with high (about 70%) pervetrence.
This section discusses 47 medical conditions causing Blue sclerae. A simple discussion of these causes with additional information is below. Causes of Blue sclerae: The following medical conditions are some of the possible causes of Blue sclerae. There are likely to be other possible causes, so ask your doctor about your symptoms.
The earliest known case of osteogenesis imperfecta (OI) is in a partially mummified infant’s skeleton from ancient Egypt now housed in the British Museum in London. In 1835, Lobstein coined the term osteogenesis imperfecta and was one of the first to correctly understand the etiology of the condition.