Web Results

ltd.aruplab.com/Tests/Pub/2001601

RNA polymerase III IgG antibody occur in about 11-23 percent of SSc patients, and typically in the absence of anti-centromere and anti-Scl-70 antibodies. A negative result indicates no detectable IgG antibodies to the dominant antigen of RNA polymerase III and does not rule out the possibility of SSc.

en.wikipedia.org/wiki/RNA_polymerase_III

In eukaryote cells, RNA polymerase III (also called Pol III) transcribes DNA to synthesize ribosomal 5S rRNA, tRNA and other small RNAs. The genes transcribed by RNA Pol III fall in the category of "housekeeping" genes whose expression is required in all cell types and most environmental conditions.

testdirectory.questdiagnostics.com/test/test-detail/19899/rna-polymerase-iii...

RNA Polymerase III Antibody - To aid in the diagnosis of systemic sclerosis. Home . RNA Polymerase III Antibody. Email. RNA Polymerase III Antibody. Test Code. 19899. CPT Code(s) 83516. Print. Test Code. 19899. CPT Code(s) 83516. Not offered in Quest Infectious Disease Inc. - San Juan Capistrano, CA.

www.ncbi.nlm.nih.gov/pmc/articles/PMC2430219

Anti-RNA polymerase III antibodies in patients with systemic sclerosis detected by indirect immunofluorescence and ELISA J. C. Parker , 1 R. W. Burlingame , 2 T. T. Webb , 2 and C. C. Bunn 1 1 Department of Clinical Immunology, Royal Free Hospital, London, UK and 2 INOVA Diagnostics Inc., San Diego, CA, USA.

academic.oup.com/rheumatology/article/48/12/1570/1786922

To evaluate the clinical usefulness of measuring anti-RNA polymerase (RNAP) III antibody with a commercially available ELISA in Japanese patients with SSc. Methods. This multicentre study involved 354 patients with SSc, 245 with non-SSc CTDs and 102 healthy controls. ELISAs were used to detect anti-RNAP III antibody, anti-topo I antibody and ACA.

www.sciencedirect.com/science/article/pii/S1568997209000342

Anti-RNA polymerase III antibodies are negatively associated to other SSc-specific autoantibodies. • Anti-RNA polymerase III antibody in SSc is a marker of rapid onset of disease and skin thickening progression.

arthritis-research.biomedcentral.com/articles/10.1186/ar4486

Among 2,177 patients with SSc, 7.1% had a history of cancer, 26% were positive for anticentromere antibodies (ACAs), 18.2% were positive for anti-Scl-70 antibodies and 26.6% were positive for anti-RNA polymerase III (anti-RNAP) antibody.

www.sciencedirect.com/science/article/abs/pii/S1568997209000342

Anti-RNA polymerase III antibodies: A marker of systemic sclerosis with rapid onset and skin thickening progression. Author links open overlay panel Ilaria Cavazzana Ceribelli Angela Airo' Paolo Zingarelli Stefania Tincani Angela Franceschini Franco. Show more.

www.ncbi.nlm.nih.gov/pubmed/25275766

Anti-RNA polymerase III antibodies in the diagnosis of scleroderma renal crisis in the absence of skin disease. Bhavsar SV(1), Carmona R. Author information: (1)From the Division of Rheumatology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

www.aruplab.com/guides/ug/tests/2001601.jsp

RNA polymerase III IgG antibody occur in about 11-23 percent of SSc patients, and typically in the absence of anti-centromere and anti-Scl-70 antibodies. A negative result indicates no detectable IgG antibodies to the dominant antigen of RNA polymerase III and does not rule out the possibility of SSc.