Anti-RNA polymerase II Antibody, clone CTD4H8; find Sigma-Aldrich-05-623 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.
There are three classes of RNA polymerase enzyme (RNAPs I, II and III). In systemic sclerosis (SSc), three main groups of anti-RNAP sera have been characterized by radioimmunoprecipitation techniques: anti-RNAP I/III sera, anti-RNAP I/II/III sera, and a group precipitating both RNAP II and topoisomerase I (topo I).
Anti-RNA polymerase III antibodies in patients with systemic sclerosis detected by indirect immunofluorescence and ELISA J. C. Parker , 1 R. W. Burlingame , 2 T. T. Webb , 2 and C. C. Bunn 1 1 Department of Clinical Immunology, Royal Free Hospital, London, UK and 2 INOVA Diagnostics Inc., San Diego, CA, USA.
RNA Polymerase III Antibody. Test Code. 19899. CPT Code(s) 83516. Print. Test Code. 19899. CPT Code(s) 83516. Not offered in Quest Infectious Disease Inc. - San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
Anti-RNA polymerase II Antibody, clone CTD4H8, Ascites Free is a highly specific mouse monoclonal antibody, that targets RNA Polymerase & has been tested in western blotting, ICC & ChIP-seq. - Find MSDS or SDS, a COA, data sheets and more information.
Anti-RNA polymerase III antibodies are negatively associated to other SSc-specific autoantibodies. • Anti-RNA polymerase III antibody in SSc is a marker of rapid onset of disease and skin thickening progression.
RNA polymerase III IgG antibody occur in about 11-23 percent of SSc patients, and typically in the absence of anti-centromere and anti-Scl-70 antibodies. A negative result indicates no detectable IgG antibodies to the dominant antigen of RNA polymerase III and does not rule out the possibility of SSc.
Goat polyclonal RNA polymerase II RPB1 antibody. Validated in WB, IP and tested in Mouse, Human. Cited in 2 publication(s). Immunogen corresponding to synthetic peptide.
The presence of circulating antinuclear antibodies (ANA) is one of the distinctive features of systemic sclerosis (SSc), or scleroderma. A variety of SSc-related ANA, including anticentromere antibody (ACA), antitopoisomerase I antibody (anti–topo I), and anti-RNA polymerase (RNAP) III antibody, have been well characterized and are used in our daily clinical practice. They are specific to ...
In eukaryote cells, RNA polymerase III (also called Pol III) transcribes DNA to synthesize ribosomal 5S rRNA, tRNA and other small RNAs. The genes transcribed by RNA Pol III fall in the category of "housekeeping" genes whose expression is required in all cell types and most environmental conditions.