The fructosamine test is similar to the hemoglobin A1c test, but it is not as commonly used.The main difference between the two tests is that the fructosamine test measures your average blood glucose level over the past two or three weeks, while the A1c test is a measurement average of your blood sugar over the past two to three months. In addition, the fructosamine test measures glycated ...
A serum fructosamine (a glycated protein) level, similar to a hemoglobin A1c level, enables assessment of long-term glycemic control in patients with diabetes mellitus. Normal values vary in relation to the serum albumin concentration and are 200-285 µmol/L, when the serum albumin concentration level is 5 g/dL.
In a similar way to hemoglobin A1c testing (which measures the glycation of hemoglobin), fructosamine testing determines the fraction of total serum proteins that have undergone glycation (the glycated serum proteins). Since albumin is the most abundant protein in blood, fructosamine levels typically reflect albumin glycation.
3) High Fructosamine Levels are Associated with Kidney Disease. In a study of more than 12k people, those with high fructosamine levels were more likely to have chronic kidney disease compared to people with normal levels . 4) High Fructosamine Levels Increase Recurrent Pregnancy Loss Risk
Fructosamine testing may be used to help people with diabetes monitor and control their blood glucose levels in cases where the A1c test cannot be used and/or a shorter-term monitoring window is desired. The level of fructosamine in the blood is a reflection of glucose levels over the previous 2-3 weeks.
If a patient has normal levels of fructosamine, then it indicates that a patient has good control of his diabetes or not diabetic. If a patient has a trend that shows fructosamine levels that travel from high to normal, then it means that the change in the treatment plan of the patient is effective. Submitted by M T on May 13, 2010 at 08:15
Because fructosamine is an indicator of the average glucose levels over the prior 2-3 week period, animals with insulin overdose and somogyi rebound can have an increased, decreased or normal fructosamine value, depending on the relative amount of time spent in the hypoglycemic state versus in the rebound hyperglycemic state..
Fructosamine is available as laboratory test which can be used as an alternative to HbA1C. The normal range for Fructosamine is 258 - 317 μmol, equivalent to an HbA1C of 6-7%.. Formulae relating Fructosamine to HbA1c have been developed in both the UK and US, as follows: Fructosamine = (A1C-1.61) x 58.82 Limitations of HbA1c
Single fructosamine measurements should be interpreted in the light of clinical signs of diabetes, body weight and blood glucose concentration. In general, the closer the fructosamine concentration is to the reference range for healthy dogs and cats, the better the glycemic control.
Glucose attaches slowly to this molecule of hemoglobin over 120 days. Glucose will attach to hemoglobin based on the amount of glucose available. Thus, a glycosolated hemoglobin lab value provides average blood glucose levels during a 1-4 month period. Fructosamine (glycated albumin) measures short term control of blood sugar for the past 1-3 ...