Web Results
rarediseases.org/rare-diseases/werdnig-hoffmann-disease

Molecular genetic testing has revealed that all types of autosomal recessive SMA are caused by disruptions or errors (mutations) in the SMN1 (survival motor ...

www.sma-europe.eu/essentials/spinal-muscular-atrophy-sma/type-1

SMA Type 1 is a life-limiting condition. Though it is not possible to accurately predict, for the majority of children (approximately 95%) life expectancy is ...

www.sma-europe.eu/essentials/spinal-muscular-atrophy-sma/what-is-spinal-muscular-atrophy

The symptoms of SMA Type 3 appear after 18 months of age. Children are able to stand and walk, though will experience reduced walking ability over time. It is a ...

kidshealth.org/en/parents/sma.html

Spinal muscular atrophy (SMA) is a condition that causes muscle weakness and ... shown significant improvement in breathing, motor function, and survival.

medlineplus.gov/genetics/condition/spinal-muscular-atrophy

... mild to moderate muscle weakness, tremors, and mild breathing problems. People with spinal muscular atrophy type IV have a normal life expectancy.

www.mountsinai.org/health-library/diseases-conditions/spinal-muscular-atrophy

Outlook (Prognosis) ... Children with SMA type I rarely live longer than 2 to 3 years because of respiratory problems and infections. Survival time with type II ...

www.nationwidechildrens.org/conditions/spinal-muscular-atrophy

Life expectancy of children with SMA type I is shortened by the many associated complications of the disease. According to current statistics, more than ...

www.medicalnewstoday.com/articles/192245

Life expectancy depends on whether breathing problems are present. Most people with SMA type 2 survive into adolescence or young adulthood. Treatment with DMTs ...

www.ajmc.com/view/dr-vamshi-rao-discusses-how-new-therapies-are-changing-physician-perceptions-on-sma-prognosis

Jan 31, 2021 ... ... Lurie Children's Hospital of Chicago, discusses how disease modifying therapies have improved spinal muscular atrophy (SMA) prognosis.

www.uptodate.com/contents/spinal-muscular-atrophy

Oct 19, 2021 ... This topic will review clinical aspects of spinal muscular atrophy (SMA), with a focus on survival motor neuron 1 (SMN1) gene-related SMA.

www.childrenshospital.org/conditions-and-treatments/conditions/s/spinal-muscular-atrophy-sma

The gene affected in SMA is the “survival of motor neuron” gene (SMN1 and SMN2). In 95 percent of SMA cases, both copies of the SMN1 gene are missing.