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Overview. Neonatal jaundice is a condition that is characterized by the yellow discoloration of the skin and sclera of the newborn due to the accumulation of unconjugated bilirubin. Unconjugated hyperbilirubinemia is usually a transient physiologic phenomenon, but if blood bilirubin rises to very high levels, kernicterus can develop.


Neonatal jaundice is the condition of elevated bilirubin at the time of birth. Bilirubin is a yellowish pigment present in hemoglobin (responsible for carrying oxygen in Red Blood Cells). An increase in the concentration of bilirubin above 3 mg per dL of blood causes neonatal jaundice.


Jaundice is the most common condition that requires medical attention and hospital readmission in newborns. [] The yellow coloration of the skin and sclera in newborns with jaundice is the result ...


Neonatal jaundice, which usually presents as an unconjugated hyperbilirubinaemia, is one of the most common physical signs observed amongst newborn infants. Approximately 60% of term newborn infants and 80% of preterm infants will have visible jaundice during the first week of life.


Jaundice is a yellow discoloration of the skin and eyes caused by hyperbilirubinemia (elevated serum bilirubin concentration). The serum bilirubin level required to cause jaundice varies with skin tone and body region, but jaundice usually becomes visible on the sclera at a level of 2 to 3 mg/dL (34 to 51 mcmol/L) and on the face at about 4 to 5 mg/dL (68 to 86 mcmol/L).


Click for pdf: Neonatal Jaundice Background The term “jaundice” comes from the root jaune, the French word for “yellow”. Jaundice is common in the neonatal period, affecting 50-60% of newborns. Jaundice is not a disease by itself, but rather, a sign that results from hyperbilirubinemia, the excessive accumulation of bilirubin in the blood.


Neonatal jaundice can affect up to 84% of term newborns and is often a benign process that is quickly corrected once identified. It is also the most common cause for hospital readmission for neonates post birth.


Neonatal jaundice and stool production in breast- or formula-fed term infants. Eur J Pediatr. 2008 May. 167(5):501-7. . Cremer RJ, Perryman PW. Influence of light on the hyperbilirubinemia of infants. Lancet. 1958. 1:1094-7. Gourley GR, Li Z, Kreamer BL, Kosorok MR. A controlled, randomized, double-blind trial of prophylaxis against jaundice ...


Introduction. Jaundice is t he yellow colouring of skin and sclera caused by the accumulation of bilirubin in the skin and mucous membranes.. Neonatal jaundice occurs in 60% of term infants and 80% of preterm infants [1] and is caused by hyperbilirubinaemia that is unconjugated (divided into physiological or pathological) or conjugated (always pathological). ). High levels of unconjugated ...


Neonatal Jaundice PHYSIOLOGIC JAUNDICE (non-pathologic unconjugated hyperbilirubinemia): 1. Term Infants: •50-60 % of all newborns are jaundiced in the first week of life. •Total serum bilirubin peaks at age 3–5 d (later in Asian infants). •Mean peak total serum bilirubin is 6 mg/dL (higher in Asian infants). 2. Preterm Infants: