Web Results
www.frontiersin.org/subjects/parp-inhibitors

Efficacy and Safety of PARP Inhibitors in Advanced or Metastatic Triple-Negative Breast Cancer: A Systematic Review and Meta- analysis.

www.cancer.gov/publications/dictionaries/cancer-terms/def/poly-adp-ribose-polymerase-inhibitor

In cancer treatment, blocking PARP may help keep cancer cells from repairing their damaged DNA, causing them to die. Poly (ADP-ribose) polymerase inhibitors are ...

academic.oup.com/pcm/article/3/3/187/5899744

PARPi exist in clinical and non-clinical varieties. There are currently five clinical inhibitors. Four of them, namely olaparib, talazoparib, niraparib, and ...

www.medscape.com/answers/1947145-155961/which-medications-in-the-drug-class-antineoplastics-parp-inhibitors-are-used-in-the-treatment-of-breast-cancer

Antineoplastics, PARP Inhibitors ... This class of agents is thought to augment cytotoxic therapy without increasing side effects and to kill cancer cells with ...

www.pennmedicine.org/news/news-releases/2021/january/discovery-could-lead-to-more-effective-parp-inhibitor-drugs-against-cancer

Jan 18, 2021 ... PARP inhibitors are recently developed drugs that have shown great promise against some types of ovarian, breast, prostate and pancreatic ...

www.eurekalert.org/news-releases/925251

Aug 12, 2021 ... Researchers pinpoint how PARP inhibitors combat BRCA1 and BRCA2 tumor ... in the U.S. News & World Report list of “America's Best Hospitals.

molecular-cancer.biomedcentral.com/articles/10.1186/s12943-020-01167-9

Mar 2, 2020 ... PARP inhibitors can trap the PARP-1 protein at a single-stranded ... and a list of related markers needs to be further validated in the ...

www.annalsofoncology.org/article/S0923-7534(19)45985-1/fulltext

Genomic instability is a hallmark of cancer, and often is the result of altered DNA repair capacities in tumour cells. DNA damage repair defects are common ...

ascopubs.org/doi/abs/10.1200/JCO.20.01924

Aug 13, 2020 ... PURPOSETo provide recommendations on the use of poly(ADP-ribose) polymerase inhibitors (PARPis) for management of epithelial ovarian, tubal, ...

www.urotoday.com/library-resources/mcrpc-treatment/122336-parp-inhibitors-a-breakthrough-in-targeted-therapies-for-prostate-cancer.html

Jun 14, 2020 ... role of PARP inhibitors in prostate cancer, adverse event of PARP ... A list of selected PARP inhibitor combination therapy trials

www.drugs.com/drug-class/parp-inhibitors.html

Poly (ADP-ribose) polymerase inhibitors, which are often called PARP inhibitors, are targeted therapies that are used to treat cancer. PARP is a protein ...