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www.mayoclinic.org/.../diagnosis-treatment/drc-20450478

Diagnosis. Your doctor may diagnose systemic mastocytosis through blood or urine tests or imaging tests like X-rays, ultrasounds, and CT scans. You may need a test to collect a sample of bone marrow to study in a lab. These tests look for high levels of mast cells or the substances they release.

www.aaaai.org/.../related-conditions/systemic-mastocytosis

Systemic Mastocytosis is a disorder where mast cells are abnormally increased in multiple organs including the bone marrow. Mast cells are immune cells that produce a variety of mediators, such as histamine, that are important in the body’s allergic responses.

en.wikipedia.org/wiki/Mastocytosis

Mastocytosis or Clonal bone marrow disorder, a type of mast cell disease, is a rare disorder affecting both children and adults caused by the accumulation of functionally defective mast cells (also called mastocytes) and CD34+ mast cell precursors.. People affected by mastocytosis are susceptible to a variety of symptoms including itching, hives, and anaphylactic shock, caused by the release ...

www.cancer.net/cancer-types/mastocytosis/diagnosis

Other tests can suggest that mastocytosis is present, but only a biopsy can make a definite diagnosis. A pathologist then analyzes the sample(s) removed during the biopsy. A pathologist is a doctor who specializes in interpreting laboratory tests and evaluating cells, tissues, and organs to diagnose disease. Bone marrow aspiration and biopsy.

tmsforacure.org/overview

OVERVIEW, DIAGNOSIS, DEFINITIONS AND CLASSIFICATION What are Mast Cells? Mast cells (MC) are immune system cells that live in the bone marrow and in body tissues, internal and external, such as the gastrointestinal tract, the lining of the airway, and the skin. Everyone has mast cells in their body, and they play many complex and […]

rarediseases.info.nih.gov/diseases/6987/mastocytosis

Mastocytosis is often first suspected by a doctor when a person has signs and symptoms of the disease. A diagnosis of mastocytosis that causes skin lesions may be confirmed by a skin biopsy of the lesion.

my.clevelandclinic.org/health/articles/5908-mastocytosis

If the diagnosis is uncertain, blood and/or urine tests may be used to measure the levels of specific chemicals or substances related to mast cells. High levels of certain substances support the diagnosis of mastocytosis. Some substances may be elevated in systemic mastocytosis, but not in cutaneous mastocytosis.

www.rightdiagnosis.com/m/mastocytosis/intro.htm

Mastocytosis: Mastocytosis is a group of disorders in both children and adults caused by the presence of too many mast cells in a person's body. Located in ... more about Mastocytosis. Mastocytosis: A disorder where excessive amounts of mast cells proliferate in organs such as the skin, liver, bone, spleen and gastrointestinal tract. Mast cells ...

www.aafp.org/afp/1999/0601/p3059.html

Mastocytosis (say “mas-toe-sigh-toe-sis”) is a rare disease of the skin (the most common form), or of other parts of the body (very rare), like the stomach, the intestines and the bone marrow ...

www.reference.com/health/mastocytosis-diagnosed-9dbb8877cb...

Doctors diagnose mastocytosis through a skin or bone marrow biopsy, according to the American Society of Clinical Oncology. Other tests, such as blood, urine and molecular tests, provide information about whether or not mastocytosis is probable, how far it has advanced, and which treatments are likely to be the most effective in its treatment.