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For multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term".


extracellular space: Abbreviation: EC space The space between cells. It contains tissue fluid, the water derived from plasma in the adjacent capillaries. The water flows among capillaries, tissue spaces, and cells. See: extracellular fluid See also: space


The extracellular space (ECS) is the microenvironment of the nerve cells and an important communication channel, allowing for long-distance extrasynaptic ‘volume’ communication by the diffusion of neuroactive substances between cells. The degree of impaired learning in aged rats and mice correlates, first, with a decrease in the ECS volume ...


The extracellular space is the space outside of the cell membrane but part of a multicellular organism. The term is typically used for a secreted protein that remains associated with the cell, e.g. as part of the extracellular matrix.


Extracellular space is the immediate external environment of brain cells. This proximity to the cell membrane makes the structure and content of the ECS important for cellular homeostasis and function.


The extracellular space surrounds cells in a multicellular organism, and is composed of two main parts: interstitial fluid (ISF) and extracellular matrix (ECM). ISF is mostly water, and has ...


Extracellular fluid (ECF) denotes all body fluid outside the cells of any multicellular organism. Total body water in healthy adults is about 60% (range 45 to 75%) of total body weight; women and the obese have a lower percentage than lean men. [citation needed] About two thirds of this is intracellular fluid within cells, and one third is the extracellular fluid.


Mutant mice deficient in hyaluronan (HA) have an epileptic phenotype. HA is one of the major constituents of the brain extracellular matrix. HA has a remarkable hydration capacity, and lack of HA causes reduced extracellular space (ECS) volume in the brain.


"Extracellular Space" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.


Extracellular space synonyms, Extracellular space pronunciation, Extracellular space translation, English dictionary definition of Extracellular space. adj. Located or occurring outside a cell or cells: extracellular fluid. ex′tra·cel′lu·lar·ly adv. adj biology situated or occurring outside a cell or cells...