Anti-parallel DNA strands are the single strands that sit at the end of each DNA molecule. One end is called the 3 prime and the other is called the 5 prime. More »

During DNA replication, the leading strand replicates continuously, while the lagging strand replicates in fragments. This occurs because replication can only occur in the 5' to 3' direction, while one of the two strands... More »

Once the DNA is separated into two strands, an RNA primer is laid down to give the new strand a place to build from so that the new enzymes can mate up to the exposed bases of the DNA and continue to build until the stra... More »

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When DNA is denatured, the hydrogen bonds that hold the double helix together break apart, separating the DNA molecule into two single strands. Denaturation occurs as the temperature increases, according to Ian VanLare, ... More »

DNA ligase is an enzyme that creates phosphodiester bonds to join complementary DNA strands. It occurs naturally in the body. Scientists use DNA ligase to engineer recombinant DNA. More »

The powerful enzyme DNA helicase unwinds the double strands of DNA by breaking the bonds between each of the complementary bases. These bases are held together by strong hydrogen bonds, but in breaking these, DNA helicas... More »

Helicase is the enzyme that is responsible for unzipping the DNA double helix and separating the strands by breaking the hydrogen bonds between them. Helicase is one of multiple enzymes working together in tandem in orde... More »