Cocaine is a highly abused drug that is most frequently detected in the urine as the metabolite benzoylecgonine and usually as part of a multiclass drug profile.
Urinary excretion of ecgonine (EC) was compared to that of cocaine, benzoylecgonine, ecgonine methyl ester and minor metabolites, ...
Understanding cocaine and metabolites urinary excretion following smoking is important for interpretation of urine test results in judicial, workplace and ...
Cocaine is a common drug of abuse. To detect its use, a screening detection concentration for the cocaine metabolite benzoylecgonine is commonly set at 150 ...
3 days ago ... Metabolites for cocaine have half-lives that range from about 15 hours to over 50 hours, and they can be detected in urine for much longer.
Apr 15, 2019 ... When a person consumes cocaine, the liver primarily converts it to the metabolites benzoylecgonine and ecgonine methyl ester.
Benzoylecgonine (BZ) and ecgonine methyl ester (EME) are the most abundant metabolites of over 11 metabolites of cocaine as shown in Fig. 17.1 [10–13].
Cocaine drug tests work not by searching for the presence of cocaine, but for proof that the body has recently metabolized (proving the ingestion of) cocaine.
Thus, mean cocaine metabolite detection times were consistent with prolonged elimination, with 63% of participants testing positive longer than the expected ...
However, what a drug test looks for is the presence of the benzoylecgonine, an inactive metabolite that has a longer half-life than cocaine. This is why tests can ...