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According to Kurtis Frank and Sol Orwell of Bodybuilding.com, creatine supplementation is generally considered to be safe for people who do not suffer from any type of kidney disorder that may cause edema or other relate... More »

While powdered creatine is stable and has a long shelf life if kept in a sealed container, experts suggest that it should be thrown away after two years. Liquid creatine begins to go bad as soon as it is opened, however,... More »

Common side effects of creatine include diarrhea, nausea, stomach pain and increased weight, according to Drugs.com. Some people may experience muscle cramping after taking creatine. Side effects may affect men or women. More »

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