Web Results


Amorolfine (or amorolfin), is a morpholine antifungal drug that inhibits Δ 14-sterol reductase and cholestenol Δ-isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes.Marketed as Curanail, Loceryl, Locetar, and Odenil, amorolfine is commonly available in the form of a nail lacquer, containing 5% amorolfine hydrochloride as the ...


Amorolfine is a medicine available in a number of countries worldwide. A list of US medications equivalent to Amorolfine is available on the Drugs.com website.


Amorolfine. Amorolfine is a morpholine derivative with antifungal and fungistatic activity, introduced in 1981. It inhibits ergosterol synthesis on two levels: by inhibiting delta 14 reductase and delta 7–8 isomerase, which affects pathogen membrane synthesis, depletes ergosterol and causes non-typical spherical sterols to accumulate in the fungal cytoplasmic membranes [].


Amorolfine nail lacquer can be sold to the public if supplied for the treatment of mild cases of distal and lateral subungual onychomycoses caused by dermatophytes, yeasts and moulds; subject to treatment of max. 2 nails, max. strength of nail lacquer amorolfine 5% and a pack size of 3 mL.


Amorolfine is used in the treatment of Fungal nail infections,Fungal skin infections. View Amorolfine’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com.


Experience with amorolfine use during pregnancy and/or lactation is limited. Only a few cases of exposure to topical amorolfine use in pregnant women have been reported in the post-authorisation setting, therefore the potential risk is unknown.


amorolfine: A drug used externally in the treatment of TINEA infection of the skin. A brand name is Loceryl.


Amorolfine is a structurally unique morpholine derivative that was introduced in the early 1980s (Haria and Bryson, 1995) (Fig. 20).It has broad fungistatic and fungicidal activity in vitro, including dermatophytes, yeasts, molds, and dimorphic fungi (Polak, 1992; De Vroey et al., 1996).Although this compound has experimental and clinical useful activity in the topical treatment of ...


Amorolfine hydrochloride is a hydrochloride resulting from the formal reacton of equimolar amounts of hydrogen chloride and amorolfine.An inhibitor of the action of squalene monooxygenase, Delta(14) reductase and D7-D8 isomerase and an antifungal agent, it is used for the topical treatment of fungal nail and skin infections. It has a role as an EC (squalene monooxygenase) inhibitor ...


Amorolfine | C21H35NO | CID 54260 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ...