As with any large airliner, the seating layout can differ based on the variant of the aircraft and the carrier operating the aircraft. It is generally separated in to first, business and economy classes.
In American Airlines' Boeing 777-200, there are a total of 45 rows distributed between the three seat classes. First class is seated in the most forward section of the aircraft. There are four rows of four seats, with two walkways segmenting them into columns in a 1-2-1 seating arrangement. Aft of first class is the business class section. There are a total of 6 rows, with the first row comprised only of tw seats in the right-most column of seats. The remaining rows are again segmented by two walkways and separated into columns in a 2-3-2 seating arrangement. The furthest 32 rows make up the economy class. The economy class is also segmented by two walkways, resulting in columns that are in a 2-5-2 seating arrangement.