The Ford F-250 averages 15 miles per gallon. Drivers report getting 10 to 15 miles per gallon around town and 15 to 20 miles per gallon on the highway, according to Kelley Blue Book. When the truck is loaded or towing, it averages fewer miles per gallon.
The Ford F-250 Super Duty is a pickup truck built to withstand heavy payloads and towing. The truck holds a 26-gallon diesel fuel tank or a 35-gallon gas fuel tank. It scores well on crash test ratings, as tested by the National Highway Traffic Safety Administration. As of 2015, prices for the F-250 range from $30,000 to $40,000, according to Kelley Blue Book.