Common problems with the Ford Expedition include engine shutoff problems in the 2006 model, transmission failure in the 2004 Expedition and bad injectors in the 2005 version. The engine shutoff issue in the 2006 model was the most-reported problem for the Expedition at CarComplaints.com, as of 2015.
The 2006 Ford Expedition experiences a glitch for some owners where the engine automatically shuts off if the fail-safe light turns on. A common solution to this problem is full replacement of the throttle body by a Ford dealership. Transmission failure in the 2004 Expedition occurs within 68,000 miles for some owners, requiring full replacement. Some 2005 Expeditions have bad injectors which result in full engine replacement to fix the problem.