As of July 2015, there is no way to shop online on Duane Reade's website. However, Duane Reade is affiliated with Walgreens, which does offer online shopping. Available products range from vitamin supplements and toys and games to kids' clothing, seasonal items and furniture.
Duane Reade-branded merchandise is available for purchase from Walgreens.com, though as of July 2015, the selection is limited to merely one item, an orthodontic pacifier. Attempts to access prescription information on Duane Reade's site link to the Walgreens site in a new window where the desired information can be found and refills can be ordered. Much of the health information on the Walgreens website is also branded as coming from Duane Reade.