As of 2015, Manny Pacquaio has faced 60 opponents in 65 fights since his professional debut in January 1995. He has faced some of the most famous names in boxing, including Oscar De La Hoya, Josh Clottey, Shane Mosely, Miguel Cotto, and, most famously, Floyd Mayweather, Jr.
Pacquiao is a native of the Philippines, and his first 15 opponents were from his home country. He didn't fight a Western opponent until the Dominican Agapito Sánchez in 2001, his 35th professional fight. As of 2015, Pacquaio has accumulated a 57-6-2 record with 38 knockouts. He has fought in eight different weight classes and held a recognized title in four of them. Because of his success, he has fought some of the biggest names in the sport. His 2015 match against Floyd Mayweather, Jr., was billed as "The Fight of the Century," which Pacquiao lost by unanimous decision. Although many fans considered the fight to be a disappointment, it earned a record 4.4 million pay-per-view buys, breaking the record set by Pacquiao and Oscar De La Hoya in 2008 (1.25 million buys). He has also fought prestigious fighters such as Ricky Hatton, Juan Manuel Marquez (twice), Timothy Bradley, Antonio Margarito and Chris Algieri.