The most notable meeting between Georgia and Missouri occurred in the 1960 Orange Bowl, in which Georgia won 14-0. Two other notable games occurred in 2013 and 2014 respectively, in which each team recorded its largest margin of victory against the other in the all-time series.
The 1960 Orange Bowl is still by the far the most high-stakes meeting between the two schools, since a major bowl championship was on the line. During those days, Missouri played in the Big Seven conference and Georgia in the Southeastern Conference, so meetings between the two schools were rare. Georgia won the game by 14 points and shut out the Tigers, thanks to tough defense and the scrambling ability of quarterback Fran Tarkenton. This was Wallace Butts' final game as the Georgia head coach.
Since Missouri joined the Southeastern Conference in 2012, the two programs meet more often than they used to. Missouri recorded its biggest victory over Georgia in 2013 with a score of 41-26, thanks to L'Damian Washington's 115 receiving yards and three different Missouri rushers reaching the end zone. Georgia bounced back in 2014 with its largest victory over Missouri in a 34-0 shutout. Georgia running back Nick Chubb recorded 143 yards on the ground and the Georgia defense came up with four interceptions off of Missouri quarterback Maty Mauk.