College football odds include point spread and moneyline wagering options on each contest. Game line odds are typically the same for either team and involve a point spread, whereas moneyline odds involve wagering on either team to win and often vary substantially.
Point spread odds are most always displayed as -110, where a stake of $110 is necessary to win $100 on either side. An example would be School A (+3.5) and School B (-3.5), meaning 3.5 points are either added or subtracted to the final score to determine the outcome, depending which side is chosen.
Moneyline odds displayed as School C (+600) and School D (-450) indicate that a $100 stake on the underdog, School C, pays $600, and a winning wager of $450 on the favorite pays just $100.