Vertebrates and invertebrates are similar in a lot of ways. Both are multicellular animals that can reproduce. They both also possess appendages, nerve chord, and have their mouth and head at one end plus anus and reproductive organ at the other end. Vertebrates and a few invertebrates belong to phylum Chordata.
Vertebrate animals and a few invertebrates within the phylum Chordata all exhibit the characteristics of chordates, which include: possession of notochord, bilateral symmetry, segmented body, pharyngeal pouches at some developmental stage and a complete digestive system. They also possess ventral heart, closed blood system and a tail at some stage of life. A few invertebrates like sea squirts are similar to vertebrates, and grow flexible rods known as notochords as embryos. The notochord develops into the vertebral column in vertebrate animals.
The cells of both vertebrates and invertebrates are not just a colony of single cells. Each one has a specific function and works together with other cells to ensure proper functioning of the organism. Invertebrate chordates, like vertebrates, possess metameric segments arranged in succession; one hollowed dorsal nerve cord; gills, which are slit-like apertures that lead from the throat region to the exterior part of the body at some stage of their lives; and a post-anal tail situated behind the anus which is not joined to any section of the gut.