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What is a simian crease?

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Quick Answer

A simian crease is a line that runs across the palm of the hand. This crease has a negative connotation, implying a likeness to a monkey or ape, so simian creases are more commonly referred to as singular transverse palmar creases.

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Full Answer

Most people have three transverse palmar creases, or three lines running across their palms. Occasionally, the three lines run together and form a single crease across the palm. Roughly 10 percent of the general population have singular transverse palmar creases. The crease is much more common among people with Down syndrome; nearly half of all people with Down syndrome have a simian crease.

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