According to the Mayo Clinic, persistent cold hands can signify nerve or circulation disorders. Chronic cold hands can also indicate tissue damage or frostbite. In many cases, cold hands are the body's way of regulating its temperature and are not a cause for concern, but it is important for individuals with consistently cold hands to consult with a medical professional.
According to WebMD, persistent cold hands can be a sign of a blood vessel disorder that inhibits blood flow to the hands. Causes of blood vessel disorders include clotting disorders, narrowing of the blood vessels and Raynaud's disease, a disorder that causes spasms of narrowing arteries of the toes and fingers. Additional signs of blood vessel disorders include blue-tinted fingers and toes, clammy skin and tingling of the arms and legs.
MedicineNet.com explains that cold hands can be triggered by circulatory or nervous system disorders, as well as hypothyroidism. Hypothyroidism is a condition in which thyroid hormone production is below normal. Common causes of hypothyroidism include thyroid destruction caused by surgery or radioactive iodine, iodine deficiencies, pituitary diseases and certain medications. Additional symptoms of hypothyroidism include depression, fatigue, dry skin, cold intolerance, sleepiness, coarse hair, leg swelling, constipation and muscle cramps. Hypothyroidism is easily treatable with hormone replacement therapy.