Gene therapy is a treatment that revolves around altering the genes inside cells to stop disease, according to Mayo Clinic. The pros include helping people fight disease or even cure their disease, while some cons are unwanted immune reactions, infections, tumors and damaging healthy cells.Continue Reading
Researchers are looking at several ways to use gene therapy, including replacing or fixing mutated genes and making diseased cells easier targets for the immune system, explains Mayo Clinic. Replacing genes that don't work correctly or no longer work at all may help treat certain diseases. Mutated genes could be turned off so they don't promote disease, and healthy genes could be turned on so they inhibit disease. Gene therapy could be used to train the immune system to better recognize cells that are a threat.
Because the new genes are delivered using a carrier that is usually a virus, the immune system might attack them and cause inflammation or organ failure, notes Mayo Clinic. It's possible the viruses may infect additional cells, and if this happens healthy cells could be damaged, causing other diseases, including cancer. Although they're altered before insertion, the viruses might recover their ability to cause disease once introduced into the body. If new genes get inserted in the wrong spot it could lead to tumor formation.Learn more about Molecular Biology & DNA
Genetic variation generally refers to the differences in genes between individual members of a population, or the frequency in which the various gene types are expressed. Genetic variation is incredibly important for the survival and adaptation of a species, as it helps in terms of natural selection and evolution.Full Answer >
Homologous chromosomes have the same genes, gene order and approximate length in common. A gene's location is called its loci. For every gene that exists at a certain loci on one homologous chromosome, the same gene exists at the same loci on the other chromosome of the homologous pair.Full Answer >
Gene therapy is an experimental technique performed by replacing a mutated gene with a healthy copy of the gene as an alternative to surgery or medications. It is designed to make a beneficial protein or introduce new genes to mutated cells to compensate for a patient's abnormal genes, explains Genetics Home Reference.Full Answer >
In terms of the human genome, the chromosome 7 pair represents more than 5 percent of all DNA and is estimated to contain up to 1,000 genes that are responsible for the production of proteins with cells, according to Genetics Home Reference. Researchers believe that genes on chromosome 7 play an important role in cellular division and growth. Chromosome 7 is also important because of the role it plays in many human diseases.Full Answer >