A polypoid lesion is a tumor that may or may not have a stalk and is located within the colon of the intestines. A polypoid lesion may be either non-neoplastic, or benign, or it may be adenomatous, or cancerous. Polypoid lesions within the colon are only diagnosed through a colonoscopy, and a lesion is generally biopsied and sent to a laboratory to determine its pathology.
A sessile polyp is a type of polypoid lesion, but it doesn't have the characteristic stalk of most polypoid lesions. Flat polyps may also be found within the colon. This type of lesion doesn't have a raised surface and can be difficult to detect from the surrounding colonic mucosa.
Most lesions found during a colonoscopy examination turn out to be polypoid lesions. A study conducted by Henry Ford Hospital found that more than half the polypoid lesions discovered during its five-year study were benign. The study found little evidence that polypoid lesions automatically lead to a colon cancer diagnosis.
However, the study found that villous adenomatous lesions generally do contain cancerous cells, especially if the adenomatous lesion is large. Resection of the lesion or resection of particular segments of the bowel may be necessary to prevent the spread of any infiltrating cancer from these types of lesions.