What Happens to Pyruvate After Glycolysis?

After glycolysis, the two pyruvates produced from one molecule of glucose are converted into acetyl CoA. This process occurs in the mitochondrion of the cell.

Cellular respiration is a series of metabolic pathways that involves the breakdown of glucose to generate usable energy in the form of adenosine triphosphate, or ATP. These pathways include glycolysis, Krebs cycle and electron transport phosphorylation.

The pyruvates from glycolysis undergo an oxidation process to produce acetyl CoA. The conversion of one molecule of pyruvate into acetyl coA can be expressed in the equation pyruvate (C3) —> CO2 + acetyl CoA (C2). Acetyl CoA is the coenzyme that drives the start of the Krebs cycle, also known as the citric acid cycle.