The first step of DNA replication occurs when a protein triggers the unwinding of the DNA helix. This is followed by a separation of the DNA strands prior to the transfer of genetic data to the newly assembled DNA strands.
A protein known as helicase is responsible for breaking down the hydrogen bonds between strands of DNA during replication. When the strands are fully separated, they are contacted by an enzyme known as primase that serves to begin the process of replication. Primase serves as a foundation for the assembly of a new DNA strand by connecting genetic materials called nucleotides together in a manner identical to the original DNA.