Fennec foxes are prey for jackals and large eagles, such as the eagle owl. Though it remains unproven, other animals thought to eat fennec foxes include hyenas, caracals and local domestic dogs.
Scientists know very little about the lives and ecology of fennec foxes, so the total number of predators that feed on the foxes remains unknown. Studies have shown that fennec foxes are quick and agile, which makes them difficult prey to catch. The fox's nocturnal behavior and physiological adaptations to the harsh desert habitat, such as large ears, sand-colored fur and the ability to survive without water for extended lengths of time, further increase the fox's chances of surviving predators.