What Are Chondroblasts?

Chondroblasts are cells that produce the components of the extracellular matrix. Chondroblasts, along with chondrocytes, are one of two cells that are responsible for producing cartilage. Chondroblasts create the major component, the extracellular matrix, of the cartilage.

When chondroblasts are trapped in the extracellular matrix that they produce, they stop producing as much matrix and become known as chrondrocytes. The function of the chondrocytes is to repair the matrix and assist with diffusion of nutrients. Overstimulation of chondroblasts can result in benign tumors known as chondroblastomas. Theses are found in areas where chondroblast activity is most active, such as the upper and lower tibia and lower humerus.