Oxygen cylinders can explode, as oxygen is very reactive, and a small increase of the chemical in the air can create a dangerous situation. One main cause of explosions in relation to oxygen includes usage of materials that are not compatible with oxygen.
Other main cause of oxygen-related explosions and fires are leaking equipment, oxygen enrichment and the careless and incorrect operation of oxygen equipment. According to the U.S. National Library of Medicine, prevention measures are encompassed by the safe handle, transport and storage of all oxygen and related devices. Oxygen cylinders should be kept in a well-ventilated area, and a clamp or chain should be used to prevent cylinders from falling over.