Bromide is a better nucleophile than chloride due to its size and the fact it is a weaker base. In terms of the leaving group, bromide is also the better atom because it is a weak base. Organic chemistry students can use a pKa table to determine the best nucleophile and leaving group.Continue Reading
Both bromide and chloride are commonly found in leaving groups. Leaving groups are the atoms or molecules left over when a chemical bond breaks during a chemical reaction. Bromide is a slightly weaker base than chloride, making it more stable during a chemical reaction.
Nucleophiles are the atoms that donate an electron pair when a bond forms.
There are four main types of nucleophiles.