Puppies require a total of six vaccines: canine distemper virus, hepatitis, leptospirosis, parainfluenza, parvovirus and coronavirus. The vaccines can be administered as individual injections or a single small volume injection called a DHLPPCv. Lyme disease and rabies vaccinations are also recommended, according to petMD.
The canine distemper virus and hepatitis vaccines prevent viral infections, notes petMD. Hepatitis primarily affects the liver.
Leptospirosis is a bacterial infection affects a puppy's kidneys. Parainfluenza can lead to upper respiratory infections in puppies. Both the Parvovirus and Coronavirus affect the lining of the intestinal track; however, Parvovirus is much more severe and is often fatal, explains petMD.
Typically, a DHLPPCv is administered as a four-shot series given about every three weeks, starting at 6 to 7 weeks of age, according to petMD.
Ideally, puppies should be taken to the vet to receive their shots before they come home, advises petMD. Every veterinarian has a preferred protocol for vaccinating puppies and providing follow-up vaccinations. Some may request a stool sample to determine if the puppy has worms.
The timing protocol may vary depending on state regulations, notes petMD. Many veterinarians believe some breeds should have two Parvo vaccines, with the second vaccine given at 20 weeks of age.