Treatment for E. Coli in dogs generally involves injections to restore body fluids, administration of a glucose solution to treat diarrhea, and antibiotics, according to PetMD. Most dogs who contract E. coli will need to be hospitalized and given emergency treatment; because a newborn puppy has an undeveloped immune system, treatment is generally unsuccessful in dogs of this age.
Following treatment for E. coli in adult dogs, restricted activity, monitoring, warmth and cage rest is necessary during the period of recovery, as stated by PetMD. Bottle feeding or even intravenous fluids may be needed to ensure that the affected dog receives adequate nutritional needs. While the dog recovers, a vet may sample the dog's blood to determine the infection status of the dog. Once home, the dog will need to be watched for any symptoms of setback and his body temperature will need to be monitored. Further treatment depends largely on the dog's progress.
For puppies, the most important way to prevent E. coli is to ensure they nurse and receive the colostrum produced by the mother dog in her first milk following birth. Changing the bedding for the litter is likewise important, as is washing the hands before handling newborn puppies that are still developing their immune systems.