What Is the Seven-in-One Puppy Vaccine?

The seven-in-one puppy vaccine is a combination shot that protects against major canine diseases including hepatitis, parvovirus and parainfluenza, states All About Goldens. Puppies need appropriate shots starting at six weeks old and should not be let off the owner’s property until receiving at least two shots.

The seven-in-one vaccine also protects against canine distemper, adenovirus cough and a few types of leptospirosis, explains All About Goldens. Puppy shots should be administered on a prescribed schedule until the animal is about 18 weeks old.

Adverse reactions to vaccines are rare, but they do occur, cautions petMD. A severe anaphylactic reaction can cause physiological problems within the animal that lead to low blood pressure, slowed heart rate and slowed breathing rate.