Use a small amount of Benadryl every eight hours to keep a cat sedated. A typical cat requires 0.5 to 2.1 milligrams per pound, but the exact dosage and health of the cat should be discussed with a veterinarian.
- Determine the appropriate amount of Benadryl
The standard dosage for felines is between 0.5 and 2.1 milligrams of Benadryl per pound of weight, but this should be determined by a veterinarian. Dosage varies with the age and general health of the feline.
- Determine the method of ingestion
Giving tablets to cats is often difficult. Hiding the tablet in a choice treat is one effective method. Another method is to hold the cat's mouth open with one hand and push the tablet as far down his throat as is feasible.
- Observe and comfort the cat
Arrange a comfortable place for the cat to lie down. Sit nearby, stroke him, and talk to him in a comforting voice. Unlike other sedatives, antihistamines like Benadryl do not cause a cat to become disoriented, so he should fall asleep rather easily. If traveling by car, it is better to have him asleep before he is put in the car.
- Give additional doses as necessary
The first dose typically lasts about eight hours. If the cat awakens and seems fretful, additional doses may be given if no adverse side effects were noted.