Hamsters squeak to communicate a variety of positive and negative emotions. It is sometimes difficult to detect the meaning of a hamster squeak, but the volume and persistence of squeaking offers clues as to what is going on. Brief, infrequent squeaks are typically an attempt at basic interaction.
Hamsters often squeak with joy when receiving a treat or engaging in activity. A more distressed, persistent squeak is more likely to be a signal that a hamster is upset, in pain or annoyed. These types of squeaks are common when a person first gets a hamster as a pet because it takes time for the animal to adapt to a new home.