The average litter size of a Chihuahua is between one and three puppies. Theoretically, a Chihuahua can have two litters of puppies a year for a period of 13 to 17 years.
Chihuahuas have small litters compared to most other dogs. It is possible for a Chihuahua to have a larger-than-average litter. A Chihuahua named Coco gave birth to a litter of 10 puppies in England in 2011.
Chihuahuas can reach sexual maturity at the age of 6 months, but most Chihuahuas are unable to have puppies until they are over 1 year old. They usually have two estrous periods a year when they mate, so it is possible for them to deliver two litters a year.