Coyotes are not apex predators and do have enemies. Wolves often drive away or kill coyotes that invade their territory, so coyotes tend to avoid areas where wolves live. Farmers and ranchers often regard coyotes as a nuisance and actively exterminate coyotes, and some people hunt coyotes for recreation.
Historically, coyotes would avoid areas where wolf packs lived. However, since the decimation of wolves in most of their historic range, coyotes have greatly expanded their range. Coyotes are now found more frequently in forested and mountainous areas, whereas previously, these regions were dominated by wolves. Coyotes have also expanded into more urban areas, where they feed on trash and household pets.