Can I Give My Puppy Benadryl?

By Staff WriterLast Updated Apr 1, 2020 5:01:44 PM ET

According to veterinarian Dr. Kara McCarty, it is safe to give a puppy Benadryl. Puppies are dosed at 1 milligram of Benadryl per pound of body weight three times a day. A 10- to 12-pound puppy can receive half of a 25 milligram Benadryl tablet three times per day.