Regularly sanitize your mattress with a combination of vacuuming, disinfecting and spot cleaning to keep it in top shape. For maximum protection, use a waterproof mattress cover or pad to minimize the mattress' contact with everyday occurrences, such as dead skin cells, sweat and any spilled liquids or crumbs.
At least once a month, remove all linens and mattress covers from the bed and thoroughly vacuum the entire mattress surface to remove any accumulated debris. For extra odor removal and sanitizing, liberally sprinkle baking soda all over the mattress before vacuuming. Take care when spot cleaning, as you don't want to get the mattress overly wet and cause mildew issues. Use a cleaning paste, such as baking soda and hydrogen peroxide, and use a gentle blot and rub method to clean any stains on the mattress surface.