Applying hairspray, rubbing alcohol or milk is an effective method of removing permanent marker stains from clothing. To obtain the maximum effectiveness for any of these methods, treat the stain as quickly as possible.
An important thing to remember when removing permanent marker from clothes is that rubbing may smear the stain into the fabric and prevent its removal. When using hairspray, dampen the stain with water, then apply a non-oily hairspray to a dry paper towel, and dab it on the stain. If the color from the permanent marker is transferring from the fabric to the towel, the method is working correctly.
When using rubbing alcohol, lay the stained material face down on a dry paper towel. Dab at the stain with a cloth soaked in rubbing alcohol. The ink should run off the fabric and onto the paper towel. Change the paper towel frequently so it can continue to absorb the ink from the marker.
When using milk, place the stained area of the fabric in milk. The milk should change color as the ink comes out of the stain. When the milk becomes discolored, replace it with a new batch of milk. Some other methods for cleaning permanent marker out of clothes include using an acetone nail polish remover or applying the commercial cleaning product Goof Off, which can be found in most department stores, to the stain.