To remove a bees' nest, first don protective clothing. If you don't have a beekeepers' outfit, wear a long-sleeved shirt, heavy pants, face mask, hat, scarf and goggles. Approach the nest after dark with a flashlight covered in red film that the bees can't see, and avoid breathing on the nest. Block up any entrance holes to the nest, then relocate the nest if possible.
More difficult nest removals sometimes require hiring a beekeeper. Beekeeper sometimes use a special vacuum to remove bees.
Alternatively, you can trap the bees. Plug up any escape holes on the nest, and make a cone from screen wire. Make sure that the opening at the narrow end of the cone is about 3/8 of an inch so that bees don't escape. Place a smaller hive provided by a beekeeper at the narrow end for the bees to move into.
Before removing a nest, first determine whether the insects are bees or wasps by examining a dead insect. Bees are fuzzy; wasps aren't. Bees are usually not aggressive unless disturbed, but a nest may need to be removed if it's in a wall or birdhouse, or if a family member is allergic to bee stings.