Carbaryl, chlorpyrifos, bendiocarb or other the synthetic pyrethroids, such as cypermethrin, cyfluthrin, lambda-cyhalothrin, are effective in killing spiders. The pesticides should be reapplied throughout the summer. Household insecticides that are intended to kill spiders when applied directly also are useful.
Insecticides can be used as a barrier treatment around the outside of the house to prevent spiders from entering the house. Insecticides should be sprayed in areas such as door thresholds, crawl space entrances, garage entrances and foundation vents. Powder or slow-release formulations also are effective for spider prevention. Glue traps are another effective method of catching and killing spiders where insecticides are not a viable method. Indoors, homeowners can set glue traps to capture spiders and use a broom or vacuum cleaner to clear out spiders and their webs and egg sacs.